Where Minutes Count We Save Hours

MindRhythm has developed a simple, disposable, cost effective headset that is designed to improve outcomes in stroke by significantly expediting time-to-treatment: the most important factor in stroke outcomes. In situations where minutes count, we save hours. MindRhythm’s Harmonyä collects and analyzes a physiology the company has named the HeadPulse™. The HeadPulse is a signal generated by minute pulsations of the brain caused by each heartbeat. This signal changes dramatically in traumatic brain injury and specifically during Large Vessel Occlusion strokes. Harmony collects the signal via a sophisticated accelerometer sensor and processes the HeadPulse through the software built into the device to determine the presence of neurologic injury. Harmony was specifically designed and tested for use in the prehospital space by emergency professionals of any skill level and easily complements existing stroke workflows. The HeadPulse data output, called a cranial accelogram, functions like “the ECG of the brain.” Harmony has been validated to identify LVO by the largest study of a prehospital stroke device ever conducted: EPISODE Detection of hEad Pulse for Ischemic StrOke DEtection Verification Study. Harmony has been proven to be easily and effectively used to identify LVO prehospital with a simple communication to the user of “LVO Y/N.” This data can be transmitted electronically to the hospital, providing the stroke team with advance notice and time to prepare for patient treatment.

CAUTION—Investigational device. Limited by Federal (or United States) law to investigational use.

STEMI for Stroke

Analogous to STEMI for heart attack, urgent evaluation of a patient with a suspected stroke is called a “Code Stroke” to underscore the time urgency for treatment. Currently there is no objective measure Emergency Medical Service (EMS) personnel can use to correctly identify an LVO stroke when responding to a Code Stroke.

Compounding this issue, different types of hospitals have varying levels of ability to treat different types of strokes. The inability to accurately triage a patient and transport them to the correct hospital has profound consequences. A patient who is sent to the wrong hospital after CT confirmation of an LVO stroke needs to be transferred to a CSC for treatment wasting precious time. During this delay, the brain is dying due to reduced blood flow, losing 2.6 years of life for every hour of delayed treatment. This is a widely known deficiency in medicine for which the stroke treatment community has been actively seeking a solution

Harmony, combined with a simple clinical examination of limb weakness, eliminates the LVO stroke triage conundrum and ensures patients are transported to the appropriate hospital, resulting in enormous benefits to patients, their families and society. Harmony is a headband placed by EMS personnel that utilizes sensors to noninvasively detect changes in brain vibrations. The Harmony algorithm requires only a minute or two of data to determine if the patient is suffering an LVO stroke.